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10.1245/ASO.2005.12.046
Annals of Surgical Oncology 12:539-545 (2005)
© 2005 Society of Surgical Oncology
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Original Article

Comparative Study of Surgical Margins in Oncoplastic Surgery and Quadrantectomy in Breast Cancer

Navneet Kaur, MD1, Jean-Yves Petit, MD1, Mario Rietjens, MD1, Fausto Maffini, MD2, Alberto Luini, MD3, Giovanna Gatti, MD3, Pier Carlo Rey, MD1, Cicero Urban, MD1 and Francesca De Lorenzi, MD, PhD1

1 Department of Plastic and Reconstructive Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141, Milan, Italy
2 Pathology Division, European Institute of Oncology, Via Ripamonti, 435, 20141, Milan, Italy
3 Breast Division, European Institute of Oncology, Via Ripamonti, 435, 20141, Milan, Italy

Correspondence: Address correspondence and reprint requests to: Jean-Yves Petit, MD; E-mail: jean.petit{at}ieo.it.

Background: Oncoplastic surgery for breast cancer is a novel concept that combines a plastic surgical procedure with breast-conserving treatment to improve the final cosmetic results. The aim of this study was to evaluate the oncological safety of oncoplastic procedures by studying the status of the surgical margins of the excised tumor specimen in comparison with standard quadrantectomies.

Methods: Thirty consecutive breast cancer patients undergoing oncoplastic surgery (group 1) and 30 patients undergoing standard quadrantectomy (group 2) were prospectively studied with regard to the stage of breast cancer, the surgical procedures performed, the volume of breast tissue excised, and the histopathology of the tumor specimen, with specific details on surgical margins.

Results: Patients who underwent oncoplastic surgery (group 1) were younger (mean age, 48.73 years) than patients who had a classic quadrantectomy (group 2; mean age, 55.76 years; P = .022). The mean volume of the excised specimen in group 1 was 200.18 cm3, compared with 117.55 cm3 in group 2 (P = .016). Surgical margins were negative in 25 cases out of 30 in group 1 and 17 out of 30 in group 2 (P = .05). The average length of the surgical margin was 8.5 mm in group 1 and 6.5 mm in group 2, but the difference was not statistically significant (P = .074).

Conclusions: Oncoplastic surgery adds to the oncological safety of breast-conserving treatment because a larger volume of breast tissue can be excised and a wider negative margin can be obtained. It is especially indicated for large tumors, for which standard breast-conserving treatment has a high probability of leaving positive margins.

Key Words: Oncoplastic surgery • Quadrantectomy • Surgical margins • Breast cancer • Plastic surgery




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Comparative Study of the Accuracy of Breast Resection in Oncoplastic Surgery and Quadrantectomy in Breast Cancer
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[Abstract] [Full Text] [PDF]


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