Annals of Surgical Oncology Cite Track
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
10.1245/ASO.2005.08.001
Annals of Surgical Oncology 12:561-569 (2005)
© 2005 Society of Surgical Oncology
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fukunaga, H.
Right arrow Articles by Monden, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fukunaga, H.
Right arrow Articles by Monden, M.

Original Article

Fusion Image of Positron Emission Tomography and Computed Tomography for the Diagnosis of Local Recurrence of Rectal Cancer

Hiroki Fukunaga, MD1, Mitsugu Sekimoto, MD, PhD1, Masataka Ikeda, MD, PhD1, Ichiro Higuchi, MD1, Masayoshi Yasui, MD1, Iwao Seshimo, MD1, Osamu Takayama, MD1, Hirofumi Yamamoto, MD, PhD1, Masayuki Ohue, MD, PhD1, Mitsuaki Tatsumi, MD, PhD2, Jun Hatazawa, MD, PhD2, Masakazu Ikenaga, MD, PhD3, Tsunehiko Nishimura, MD, PhD4 and Morito Monden, MD, PhD1

1 Department of Surgery and Clinical Oncology (E2), Graduate School of Medicine, Osaka University, 2-2 Yamadaoka Suita, Kinetics (D9), Osaka 565-0871, Japan
2 Department of Nuclear Medicine and Tracer Kinetics (D9), Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
3 Department of Surgery, Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka 540-0006, Osaka, Japan
4 Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii, Kawaramachi-Hirokoji, Kamigyo, Kyoto 602-8566, Japan

Correspondence: Address correspondence and reprint requests to: Mitsugu Sekimoto, MD, PhD; E-mail: sekimoto{at}surg2.med.osaka-u.ac.jp.

Background: The aim of this study was to evaluate the clinical and therapeutic value of digital fusion image (FI) of positron emission tomography (PET) using 18F-fluorodeoxy glucose and computed tomography (CT) in patients who were suspected of having a local recurrence of rectal cancer.

Methods:: Forty-two patients (32 men and 10 women; mean age, 61.4 years, range, 40–79 years) with a suspicion of local recurrence after curative resection of rectal cancer were prospectively recruited and underwent 18F-fluorodeoxy glucose-PET and CT. The FI was reconstructed with a commercially available digital software program, T-B Fusion. Wilcoxon signed rank test was used to compare FI with CT alone or PET alone.

Results: FI yielded a correct diagnosis in 39 (93%) of 42 patients, whereas CT alone and PET alone did so in 33 (79%) and 37 (88%) patients, respectively. FI had better diagnostic accuracy than CT alone (P = .0138) and PET alone (P = .0156). Overall, FI altered patient management in 11 (26.2%) patients on the basis of additional information, including differentiation of the tumor from the postoperative scar in 6 patients, exact anatomical location in 3 patients, and both in 2 patients.

Conclusions: FI has a potential clinical value in the treatment of suspected local recurrence of rectal cancer.

Key Words: PET • CT • Fusion image • Local recurrence of rectal cancer




This article has been cited by other articles:


Home page
 Am. J. Roentgenol.Home page
C. Capirci, D. Rubello, F. Chierichetti, G. Crepaldi, S. Fanti, G. Mandoliti, S. Salviato, G. Boni, L. Rampin, C. Polico, et al.
Long-term prognostic value of 18F-FDG PET in patients with locally advanced rectal cancer previously treated with neoadjuvant radiochemotherapy.
Am. J. Roentgenol., August 1, 2006; 187(2): W202 - W208.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the Society of Surgical Oncology.