Annals of Surgical Oncology Cite Track
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
10.1245/s10434-006-9055-3
Annals of Surgical Oncology 14:195-201 (2007)
© 2007 Society of Surgical Oncology
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Capussotti, L.
Right arrow Articles by Polastri, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Capussotti, L.
Right arrow Articles by Polastri, R.

Original Article

Major Liver Resections Synchronous with Colorectal Surgery

Lorenzo Capussotti, MD, Alessandro Ferrero, MD, Luca Viganò, MD, Dario Ribero, MD, Roberto Lo Tesoriere, MD and Roberto Polastri, MD

Unit of Surgical Oncology, Institute for Cancer Research and Treatment, Strada Provinciale 142 km 3, 95 10060, Candiolo, Torino, Italy

Correspondence: Address correspondence and reprint requests to: Lorenzo Capussotti, MD; E-mail: lcapussotti{at}mauriziano.it

Background: Surgical strategy in liver metastases synchronous to colorectal cancer remains controversial. The aim of this study was to evaluate feasibility and short-term outcomes of major hepatectomies synchronous to colorectal surgery.

Methods: Between January 1985 and December 2004, 79 patients underwent major hepatectomy for metastases synchronous to colorectal cancer; 31 underwent synchronous hepatectomy and colorectal surgery, and 48 underwent delayed liver resection.

Results: The synchronous group had a higher rate of right colectomy (38.7% vs. 18.8%, P = .0499) and larger metastases (8 vs. 5.3 cm, P = .0032). Mortality (one patient in synchronous group), morbidity, and anastomotic leak rates were similar in the two groups. Colon-related morbidity did not cause adjunctive liver complications. Hospitalization in delayed hepatectomies was shorter (10.4 days vs. 13.9 days, P = .0021). Blood and plasma transfusions were higher in synchronous resections (41.9% vs. 16.7%, P = .0131 and 54.8% vs. 31.3%, P = .0370); no differences were found in the last 10 years. Considering both surgical procedures (colorectal + liver resection), in delayed hepatectomies, morbidity was higher (56.3% vs. 32.6%, P = .0369) and hospitalization was longer (20.5 vs. 13.9 days, P = .00001). Nine patients underwent major hepatectomy at the same time as anterior rectal resection with no mortality (morbidity 22.2%, mean hospitalization 12.4 days).

Conclusions: Major hepatectomies can be safely performed at the same time as colorectal surgery in selected patients with synchronous metastases with similar short-term results, even in the presence of rectal cancer.

Key Words: Colorectal liver metastases • Synchronous liver metastases • Liver surgery • Synchronous liver resection




This article has been cited by other articles:


Home page
 Ann. Surg. Oncol.Home page
S. K. Reddy, T. M. Pawlik, D. Zorzi, A. L. Gleisner, D. Ribero, L. Assumpcao, A. S. Barbas, E. K. Abdalla, M. A. Choti, J.-N. Vauthey, et al.
Simultaneous Resections of Colorectal Cancer and Synchronous Liver Metastases: A Multi-institutional Analysis
Ann. Surg. Oncol., December 1, 2007; 14(12): 3481 - 3491.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the Society of Surgical Oncology.